Princeton ACS Meeting and Evening Session of the 2017 NMR Symposium
In Conjunction with the NJACS NMR Topical Group
Thursday, October 19, 2017
David Foley, PhD, Principal Scientist, Analytical Research & Development, Pfizer Global Research & Development will speak on
“Developing Chemical Reactions using NMR Spectroscopy”
Frick Chemistry Laboratory, Princeton University. Mixer 5:15 pm; Lecture 6:00 pm; Dinner 6;45
Abstract: While biotechnological advances, genomics and high throughput screenings or combinatorial and asymmetric syntheses have opened new vistas in drug discovery, the industry is facing a serious innovation deficit. Critics suggest that “we have become high throughput in technology, yet have remained low throughput in thinking”. Post marketing failures of blockbuster drugs have become major concerns of industries, leading to a significant shift in paradigms and integration of discovery and process research.
Process Chemistry / Route Selection are pivotal activities in the path of a drug from concept to commercialization. The development of a novel, cost efficacious, scalable processes for chiral molecules natural and synthetic will be presented. Also, several problems are currently associated with the use of biological systems in studying drug metabolism. Some novel approaches will be discussed.
Biography: Dr. Foley received his BS degree and PhD in organic chemistry from University College Cork, Ireland, 2008. He then held postdoctoral positions at Eli Lilly, Indianapolis, IN where he focused on NMR for the elucidation of organic reaction mechanisms, and at Pfizer, Groton, CT where he worked on the development of an NMR reaction monitoring platform. In 2012, he joined Pfizer as Principal Research Scientist in the Structural Elucidation Group where he continues to work on reaction monitoring and characterization using online NMR.
Reservations: The meeting will be held in Frick Laboratory, Princeton University. The social mixer will begin at 5:15 pm in the CaFe area of Taylor Commons. The lecture will be held in the Auditorium at 6:00 pm followed by dinner in Taylor Commons (CaFe area) at 6:45 pm. Frick Laboratory is located at the east end of the pedestrian bridge on Washington Rd, adjacent to the Weaver Track and Field Stadium. Parking is available in Lot 21, corner of Faculty Road and Fitzrandolph Road or other lots along Ivy Lane (see http://m.princeton.edu/map/). The seminar is free and open to the public. Reservations are required for dinner, which is $20 ($10 for students). Please contact Louise Lawter at firstname.lastname@example.org or 215-428-1475 by October 13 to make reservations. Reservations must be canceled no later than October 18 to avoid being billed for the dinner.
For more information on the complete NMR Symposium and to register go to http://www.njacs.org/nmr-spectroscopy-topical-group