The Princeton ACS Protein Symposium, Frick Laboratories, Princeton University
Computational design of proteins with new and useful functions
Christina Vizcarra, PhD, Assistant Professor of Chemistry, Barnard College, New York, NY
The impressive variety of things that proteins do in our bodies – from metabolizing food to powering muscle contractions and much more – has sparked interest in creating proteins that carry out novel functions. These functions could be useful in agriculture, nanotechnology, or medicine. In this talk, I will discuss one approach to protein engineering: computational design. This method has been used to create novel proteins and has also shown us how much we have to learn about these amazing biomolecules.
Educational resources pertinent to the Protein Symposium keynote presentation
“Designer Proteins” article from PDB-101, RCSB PDB Molecule of the Month by David S. Goodsell
Introductory lecture from iBiology on protein design by David Baker
Frontiers lecture on directed evolution The Expanding Enzyme Universe by Frances Arnold
Solve Protein puzzles with FoldIt
Acknowledgements: Princeton ACS received support for a protein symposium for high school science educators and their students on 17May2018 from ACS as a Local Section Innovative Project Grant and on 09June2018 from The Company of Biologists (www.biologists.com) as a Small Meeting Grant (Barbara Ameer, grant applicant)
More about the Protein Symposium Launch in Spring 2018
A new PACS outreach event in 2018 will be a series of talks related to proteins, given by graduate students, post-docs and other guest scientists. The intent is to interest high school students in taking on projects about proteins in their course work or as extracurricular activities. In fact, “Proteins/Protein Engineering” is now in the Chemagination at Princeton competition as a fifth category.
The protein symposium will be at Princeton University on Saturday, May 19th. Preference will be given to high school science departments in the Princeton vicinity and other areas provided they communicate their intent to participate to Dr. Barbara Ameer via email at email@example.com no later than April 15th. Space is limited.